HLA-DRA antibody (AA 26-254)
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- Target See all HLA-DRA Antibodies
- HLA-DRA (HLA Class II DR alpha (HLA-DRA))
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Binding Specificity
- AA 26-254
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This HLA-DRA antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)
- Purpose
- HLA-DRA Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human HLA-DRA (AA: 26-254) expressed in E. Coli.
- Clone
- 1C11A5
- Isotype
- IgG2b
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anti-HLA Class II DR alpha (HLA-DRA) (AA 26-216) antibody
HLA-DRA Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 27-216) antibodyHLA-DRA Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA Reactivity: Human, Mouse, Rat WB, IHC, IF, ELISA, ICC Host: Rabbit Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 48-75), (N-Term) antibodyHLA-DRA Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB19526 unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 1-254) antibodyHLA-DRA Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA Reactivity: Human IHC, FACS, IF, StM Host: Mouse Monoclonal 19-26-1-same as MB-26-1 unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA Reactivity: Human IHC Host: Rabbit Monoclonal MSVA-470R unconjugated Recombinant Antibody
anti-HLA Class II DR alpha (HLA-DRA) (AA 26-221) antibodyHLA-DRA Reactivity: Rabbit WB, IHC, IP, ICC Host: Guinea Pig Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 149-177), (C-Term) antibodyHLA-DRA Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB19527 unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/100 - 1/500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- HLA-DRA (HLA Class II DR alpha (HLA-DRA))
- Alternative Name
- HLA-DRA (HLA-DRA Products)
- Synonyms
- HLA-DRA1 antibody, MLRW antibody, DR-alpha antibody, HLA-DRA antibody, Mamu-DRA1 antibody, major histocompatibility complex, class II, DR alpha L homeolog antibody, major histocompatibility complex, class II, DR alpha antibody, hla-dra.L antibody, HLA-DRA antibody, MAMU-DRA antibody, BOLA-DRA antibody
- Background
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Description: HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
Aliases: MLRW, HLA-DRA1
- Molecular Weight
- 28.6kDa
- Gene ID
- 3122
- HGNC
- 3858
- UniProt
- P01903
- Pathways
- TCR Signaling, CXCR4-mediated Signaling Events, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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