KDM2B antibody (AA 457-555)

Catalog No. ABIN5542613

Product Details anti-KDM2B Antibody

Target: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Binding Specificity: AA 457-555

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KDM2B antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: FBXL10 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human FBXL10 (AA: 457-555) expressed in E. Coli.

Clone: 3B7D11

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for KDM2B

Target: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Alternative Name: FBXL10 (KDM2B Products)

Background:

Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.

Aliases: CXXC2, Fbl10, PCCX2, FBXL10, JHDM1B

Molecular Weight: 152.6kDa

Gene ID: 84678

HGNC: 84678

UniProt: Q8NHM5

Pathways: Tube Formation, Warburg Effect