Caspase 7 antibody (AA 29-198)
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- Target See all Caspase 7 (CASP7) Antibodies
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
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Binding Specificity
- AA 29-198
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Caspase 7 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
- Purpose
- CASP-7 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CASP-7 (AA: 29-198) expressed in E. Coli.
- Clone
- 4D10B2
- Isotype
- IgG1
- Top Product
- Discover our top product CASP7 Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
- Alternative Name
- CASP-7 (CASP7 Products)
- Background
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Description: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Aliases: MCH3, CMH-1, LICE2, CASP7, ICE-LAP3
- Molecular Weight
- 34.3kDa
- Gene ID
- 840
- HGNC
- 840
- UniProt
- P55210
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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