PDGFRB antibody (AA 33-133)
-
- Target See all PDGFRB Antibodies
- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
-
Binding Specificity
- AA 33-133
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This PDGFRB antibody is un-conjugated
-
Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- PDGFRB Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human PDGFRB (AA: 33-133) expressed in E. Coli.
- Clone
- 2G7B7
- Isotype
- IgG1
- Top Product
- Discover our top product PDGFRB Primary Antibody
-
-
- Application Notes
-
ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
- Target
- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
- Alternative Name
- PDGFRB (PDGFRB Products)
- Background
-
Description: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Aliases: IMF1, IBGC4, JTK12, PDGFR, CD140B, PDGFR1, PDGFR-1
- Molecular Weight
- 124kDa
- Gene ID
- 5159
- HGNC
- 5159
- UniProt
- P09619
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
-