TdT antibody (AA 52-192)

Catalog No. ABIN5542550

Product Details anti-TdT Antibody

Target: TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Binding Specificity: AA 52-192

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TdT antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: DNTT Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human DNTT (AA: 52-192) expressed in E. Coli.

Clone: 4B10C3

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for TdT

Target: TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Alternative Name: DNTT (DNTT Products)

Synonyms: TdT antibody, TDT antibody, BB160593 antibody, Tdt antibody, dntt-A antibody, dntt antibody, DNA nucleotidylexotransferase antibody, deoxynucleotidyltransferase, terminal antibody, DNA nucleotidylexotransferase L homeolog antibody, terminal deoxynucleotidyl transferase antibody, DNTT antibody, dntt antibody, Dntt antibody, dntt.L antibody, tdt antibody

Background:

Description: This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Aliases: TDT

Molecular Weight: 58.5kDa

Gene ID: 1791

HGNC: 1791

UniProt: P04053

Pathways: DNA Damage Repair