YWHAB antibody (AA 1-246)

Catalog No. ABIN5542549

Product Details anti-YWHAB Antibody

Target: YWHAB (14-3-3 alpha + beta (YWHAB))

Binding Specificity: AA 1-246

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This YWHAB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purpose: YWHAB Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human YWHAB (AA: 1-246) expressed in E. Coli.

Clone: 5B5G10

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for YWHAB

Target: YWHAB (14-3-3 alpha + beta (YWHAB))

Alternative Name: YWHAB (YWHAB Products)

Background:

Description: This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.

Aliases: HS1, GW128, YWHAA, KCIP-1, HEL-S-1

Molecular Weight: 28kDa

Gene ID: 7529

HGNC: 7529

UniProt: P31946

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location