NOTCH3 antibody (AA 47-156)
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- Target See all NOTCH3 Antibodies
- NOTCH3 (Notch 3 (NOTCH3))
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Binding Specificity
- AA 47-156
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This NOTCH3 antibody is un-conjugated
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Application
- ELISA
- Purpose
- Notch3 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human Notch3 (AA: 47-156) expressed in E. Coli.
- Clone
- 2E4D11
- Isotype
- IgG2b
- Top Product
- Discover our top product NOTCH3 Primary Antibody
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- Application Notes
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- NOTCH3 (Notch 3 (NOTCH3))
- Alternative Name
- Notch3 (NOTCH3 Products)
- Synonyms
- CADASIL antibody, CASIL antibody, IMF2 antibody, AW229011 antibody, N3 antibody, hpbk antibody, fa14b08 antibody, notch5 antibody, wu:fa14b08 antibody, notch 3 antibody, NOTCH3 antibody, Notch3 antibody, notch3 antibody
- Background
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Description: This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Aliases: IMF2, CASIL, CADASIL
- Molecular Weight
- 243.6kDa
- Gene ID
- 4854
- HGNC
- 4854
- UniProt
- Q9UM47
- Pathways
- Notch Signaling
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