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NOTCH3 antibody (AA 47-156)

NOTCH3 Reactivity: Human ELISA Host: Mouse Monoclonal 2E4D11 unconjugated
Catalog No. ABIN5542533
  • Target See all NOTCH3 Antibodies
    NOTCH3 (Notch 3 (NOTCH3))
    Binding Specificity
    • 14
    • 11
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 47-156
    Reactivity
    • 49
    • 17
    • 11
    • 1
    Human
    Host
    • 34
    • 15
    • 3
    • 1
    • 1
    Mouse
    Clonality
    • 38
    • 17
    Monoclonal
    Conjugate
    • 29
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOTCH3 antibody is un-conjugated
    Application
    • 26
    • 23
    • 20
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    ELISA
    Purpose
    Notch3 Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human Notch3 (AA: 47-156) expressed in E. Coli.
    Clone
    2E4D11
    Isotype
    IgG2b
    Top Product
    Discover our top product NOTCH3 Primary Antibody
  • Application Notes
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    NOTCH3 (Notch 3 (NOTCH3))
    Alternative Name
    Notch3 (NOTCH3 Products)
    Synonyms
    CADASIL antibody, CASIL antibody, IMF2 antibody, AW229011 antibody, N3 antibody, hpbk antibody, fa14b08 antibody, notch5 antibody, wu:fa14b08 antibody, notch 3 antibody, NOTCH3 antibody, Notch3 antibody, notch3 antibody
    Background

    Description: This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

    Aliases: IMF2, CASIL, CADASIL

    Molecular Weight
    243.6kDa
    Gene ID
    4854
    HGNC
    4854
    UniProt
    Q9UM47
    Pathways
    Notch Signaling
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