MITF antibody (AA 1-114)

Catalog No. ABIN5542530

Product Details anti-MITF Antibody

Target: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Binding Specificity: AA 1-114

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MITF antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Purpose: MITF Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human MITF (AA: 1-114) expressed in E. Coli.

Clone: 3A2E2

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for MITF

Target: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Alternative Name: MITF (MITF Products)

Background:

Description: This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Aliases: MI, WS2, CMM8, WS2A, bHLHe32

Molecular Weight: 58.8kDa

Gene ID: 4286

HGNC: 3106

UniProt: O75030

Pathways: Chromatin Binding