LEF1 antibody (AA 33-138)
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- Target See all LEF1 Antibodies
- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
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Binding Specificity
- AA 33-138
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This LEF1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purpose
- LEF1 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human LEF1 (AA: 33-138) expressed in E. Coli.
- Clone
- 1A4B11
- Isotype
- IgG1
- Top Product
- Discover our top product LEF1 Primary Antibody
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- Application Notes
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))
- Alternative Name
- LEF1 (LEF1 Products)
- Synonyms
- LEF1 antibody, 3000002B05 antibody, AI451430 antibody, Lef-1 antibody, LEF-1 antibody, TCF10 antibody, TCF1ALPHA antibody, TCF7L3 antibody, lymphoid enhancer binding factor 1 antibody, lymphoid enhancer-binding factor 1 antibody, lymphoid enhancer factor XLEF-1B antibody, LEF1 antibody, lef1 antibody, Lef1 antibody
- Background
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Description: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
Aliases: LEF-1, TCF10, TCF7L3, TCF1ALPHA
- Molecular Weight
- 44.2kDa
- Gene ID
- 51176
- HGNC
- 51176
- UniProt
- Q9UJU2
- Pathways
- WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
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