IRAK3 antibody (AA 454-596)
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- Target See all IRAK3 Antibodies
- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
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Binding Specificity
- AA 454-596
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IRAK3 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Purpose
- IRAK3 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human IRAK3 (AA: 454-596) expressed in E. Coli.
- Clone
- 6G9G2
- Isotype
- IgG1
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
- Alternative Name
- IRAK3 (IRAK3 Products)
- Synonyms
- IRAK3 antibody, si:dkey-150i15.2 antibody, ASRT5 antibody, IRAKM antibody, IrakM antibody, 4833428C18Rik antibody, AI563835 antibody, IRAK-M antibody, interleukin 1 receptor associated kinase 3 antibody, interleukin-1 receptor-associated kinase 3 antibody, IRAK3 antibody, irak3 antibody, Irak3 antibody
- Background
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Description: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
Aliases: ASRT5, IRAKM
- Molecular Weight
- 67.8kDa
- Gene ID
- 11213
- HGNC
- 11213
- UniProt
- Q9Y616
- Pathways
- TLR Signaling, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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