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DNMT3B antibody (AA 1-150)

DNMT3B Reactivity: Human IHC, ELISA, FACS Host: Mouse Monoclonal 7E5E9C1 unconjugated
Catalog No. ABIN5542518
  • Target See all DNMT3B Antibodies
    DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
    Binding Specificity
    • 18
    • 16
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-150
    Reactivity
    • 85
    • 53
    • 32
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 82
    • 5
    • 2
    • 1
    Mouse
    Clonality
    • 76
    • 14
    Monoclonal
    Conjugate
    • 35
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This DNMT3B antibody is un-conjugated
    Application
    • 72
    • 35
    • 23
    • 20
    • 13
    • 13
    • 11
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
    Purpose
    DNMT3B Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human DNMT3B (AA: 1-150) expressed in E. Coli.
    Clone
    7E5E9C1
    Isotype
    IgG1
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
    Alternative Name
    DNMT3B (DNMT3B Products)
    Synonyms
    DNMT3B antibody, LOC100218113 antibody, ICF antibody, ICF1 antibody, M.HsaIIIB antibody, MmuIIIB antibody, cb91 antibody, dnmt3bl antibody, dnmt7 antibody, sb:cb91 antibody, wu:fb16h07 antibody, DNA methyltransferase 3 beta antibody, DNA methyltransferase 3B antibody, DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a antibody, DNMT3B antibody, Dnmt3b antibody, dnmt3b antibody, dnmt3ba antibody
    Background

    Description: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

    Aliases: ICF, ICF1, M.HsaIIIB

    Molecular Weight
    95.8kDa
    Gene ID
    1789
    HGNC
    1789
    UniProt
    Q9UBC3
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