DNMT3A antibody (AA 46-180)
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- Target See all DNMT3A Antibodies
- DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
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Binding Specificity
- AA 46-180
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This DNMT3A antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Purpose
- DNMT3A Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human DNMT3A (AA: 46-180) expressed in E. Coli.
- Clone
- 4G5F11
- Isotype
- IgG2a
- Top Product
- Discover our top product DNMT3A Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
- Alternative Name
- DNMT3A (DNMT3A Products)
- Synonyms
- DNMT3A antibody, DNMT3A2 antibody, M.HsaIIIA antibody, MmuIIIA antibody, dnmt3a1 antibody, dnmt6 antibody, DNA methyltransferase 3 alpha antibody, DNA methyltransferase 3A antibody, DNA (cytosine-5-)-methyltransferase 3 alpha b antibody, DNMT3A antibody, Dnmt3a antibody, dnmt3a antibody, dnmt3ab antibody
- Background
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Description: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.
Aliases: TBRS, DNMT3A2, M.HsaIIIA
- Molecular Weight
- 102kDa
- Gene ID
- 1788
- HGNC
- 1788
- UniProt
- Q9Y6K1
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