DDX5 antibody (AA 475-614)

Catalog No. ABIN5542510

Product Details anti-DDX5 Antibody

Target: DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))

Binding Specificity: AA 475-614

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DDX5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purpose: DDX5 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human DDX5 (AA: 475-614) expressed in E. Coli.

Clone: 4F1C12

Isotype: IgG2a

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for DDX5

Target: DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))

Alternative Name: DDX5 (DDX5 Products)

Synonyms: G17P1 antibody, HLR1 antibody, HUMP68 antibody, p68 antibody, 2600009A06Rik antibody, Hlr1 antibody, wu:fa56a07 antibody, wu:fb11e01 antibody, wu:fb16c10 antibody, wu:fb53b05 antibody, ddx5 antibody, DEAD-box helicase 5 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 antibody, DEAD (Asp-Glu-Ala-Asp) box helicase 5 antibody, DEAD-box helicase 5 L homeolog antibody, DDX5 antibody, Ddx5 antibody, ddx5 antibody, ddx5.L antibody

Background:

Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. This gene consists of 13 exons, and alternatively spliced transcripts containing several intron sequences have been detected, but no isoforms encoded by these transcripts have been identified.

Aliases: p68, HLR1, G17P1, HUMP68

Molecular Weight: 69.1kDa

Gene ID: 1655

HGNC: 1655

UniProt: P17844

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus