MAPK10 antibody (AA 180-329)
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- Target See all MAPK10 Antibodies
- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
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Binding Specificity
- AA 180-329
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This MAPK10 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purpose
- MAPK10 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human MAPK10 (AA: 180-329) expressed in E. Coli.
- Clone
- 2B10H12
- Isotype
- IgG2a
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- Application Notes
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
- Alternative Name
- MAPK10 (MAPK10 Products)
- Background
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Description: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
Aliases: JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK
- Molecular Weight
- 52.6kDa
- Gene ID
- 5602
- HGNC
- 5602
- UniProt
- P53779
- Pathways
- MAPK Signaling, WNT Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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