BAD antibody (AA 1-168)
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- Target See all BAD Antibodies
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
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Binding Specificity
- AA 1-168
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This BAD antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Purpose
- BAD Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human BAD (AA: FULL(1-168)) expressed in E. Coli.
- Clone
- 1G5B3
- Isotype
- IgG1
- Top Product
- Discover our top product BAD Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
- Alternative Name
- BAD (BAD Products)
- Background
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Description: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Aliases: BBC2, BCL2L8
- Molecular Weight
- 18.4kDa
- Gene ID
- 572
- HGNC
- 572
- UniProt
- Q92934
- Pathways
- MAPK Signaling, PI3K-Akt Signaling, RTK Signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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