CBX1 antibody (AA 1-185)

Catalog No. ABIN5542477

Product Details anti-CBX1 Antibody

Target: CBX1 (Chromobox Homolog 1 (CBX1))

Binding Specificity: AA 1-185

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CBX1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purpose: CBX1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CBX1 (AA: 1-185) expressed in E. Coli.

Clone: 4D7B8

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CBX1

Target: CBX1 (Chromobox Homolog 1 (CBX1))

Alternative Name: CBX1 (CBX1 Products)

Synonyms: CBX antibody, HP1-BETA antibody, HP1Hs-beta antibody, HP1Hsbeta antibody, M31 antibody, MOD1 antibody, p25beta antibody, Cbx antibody, Cbx-rs2 antibody, E430007M08Rik antibody, HP1B antibody, Hp1beta antibody, cbx1 antibody, wu:fe14b09 antibody, zgc:55739 antibody, zgc:86924 antibody, chromobox 1 antibody, chromobox homolog 1a (HP1 beta homolog Drosophila) antibody, chromobox 1 S homeolog antibody, chromobox homolog 1b (HP1 beta homolog Drosophila) antibody, CBX1 antibody, Cbx1 antibody, cbx1a antibody, cbx1.S antibody, cbx1b antibody

Background:

Description: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Aliases: CBX, M31, MOD1, p25beta, HP1-BETA, HP1Hsbeta, HP1Hs-beta

Molecular Weight: 21.4kDa

Gene ID: 10951

HGNC: 10951

UniProt: P83916