RAP1GAP antibody (AA 412-660)
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- Target See all RAP1GAP Antibodies
- RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))
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Binding Specificity
- AA 412-660
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This RAP1GAP antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- RAP1GAP Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human RAP1GAP (AA: 412-660) expressed in E. Coli.
- Clone
- 2G7B6
- Isotype
- IgG2b
- Top Product
- Discover our top product RAP1GAP Primary Antibody
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anti-RAP1 GTPase Activating Protein (RAP1GAP) (Internal Region) antibody
RAP1GAP Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) (AA 412-678) antibodyRAP1GAP Reactivity: Human Host: Mouse Monoclonal unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) (C-Term) antibodyRAP1GAP Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) (C-Term) antibodyRAP1GAP Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) antibodyRAP1GAP Reactivity: Human WB, IF Host: Rabbit Monoclonal unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) (C-Term) antibodyRAP1GAP Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) (AA 451-550) antibodyRAP1GAP Reactivity: Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) (AA 105-128) antibodyRAP1GAP Reactivity: Human WB Host: Rabbit Polyclonal RB53561 unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) (AA 503-552) antibodyRAP1GAP Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Bat, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-RAP1 GTPase Activating Protein (RAP1GAP) (C-Term) antibodyRAP1GAP Reactivity: Human, Mouse, Cow, Guinea Pig, Horse, Bat, Monkey WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))
- Alternative Name
- RAP1GAP (RAP1GAP Products)
- Background
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Description: This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins.
Aliases: RAPGAP, RAP1GA1, RAP1GAP1, RAP1GAPII
- Molecular Weight
- 73.4kDa
- Gene ID
- 5909
- HGNC
- 5909
- UniProt
- P47736
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