Cytokeratin 5 antibody (AA 258-357)

Catalog No. ABIN5542459

Product Details anti-Cytokeratin 5 Antibody

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Binding Specificity: AA 258-357

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cytokeratin 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purpose: CK5 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CK5 (AA: 258-357) expressed in E. Coli.

Clone: 2C8E4

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Cytokeratin 5

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Alternative Name: CK5 (KRT5 Products)

Background:

Description: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Aliases: KRT5, K5, DDD, DDD1, EBS2, KRT5A

Molecular Weight: 62.4kDa

Gene ID: 3852

HGNC: 3852

UniProt: P13647