SIRT6 antibody (AA 141-250)

Catalog No. ABIN5542442

Product Details anti-SIRT6 Antibody

Target: SIRT6 (Sirtuin 6 (SIRT6))

Binding Specificity: AA 141-250

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIRT6 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purpose: SIRT6 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human SIRT6 (AA: 141-250) expressed in E. Coli.

Clone: 2G1H1

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for SIRT6

Target: SIRT6 (Sirtuin 6 (SIRT6))

Alternative Name: SIRT6 (SIRT6 Products)

Background:

Description: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.

Aliases: SIR2L6

Molecular Weight: 39kDa

Gene ID: 51548

HGNC: 51548

UniProt: Q8N6T7