MIB1 antibody (AA 6-221)

Catalog No. ABIN5542434

Product Details anti-MIB1 Antibody

Target: MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))

Binding Specificity: AA 6-221

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MIB1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Purpose: MIB1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human MIB1 (AA: 6-221) expressed in E. Coli.

Clone: 2A7B1

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for MIB1

Target: MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))

Alternative Name: MIB1 (MIB1 Products)

Background:

Description: This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).

Aliases: MIB, DIP1, ZZZ6, DIP-1, LVNC7, ZZANK2

Molecular Weight: 110kDa

Gene ID: 57534

HGNC: 4741

UniProt: Q86YT6

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection