OB Cadherin antibody (AA 468-617)
-
- Target See all OB Cadherin (CDH11) Antibodies
- OB Cadherin (CDH11) (Cadherin 11 (CDH11))
-
Binding Specificity
- AA 468-617
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This OB Cadherin antibody is un-conjugated
-
Application
- ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Purpose
- CDH11 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CDH11 (AA: 468-617) expressed in E. Coli.
- Clone
- 4E12G10
- Isotype
- IgG1
-
-
- Application Notes
-
ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
- Target
- OB Cadherin (CDH11) (Cadherin 11 (CDH11))
- Alternative Name
- CDH11 (CDH11 Products)
- Synonyms
- cad11 antibody, cdhob antibody, osf-4 antibody, Xcad-11 antibody, MGC108014 antibody, OB-cadherin antibody, cadherin-11 antibody, Cad11 antibody, cdhvn antibody, vnc antibody, CAD11 antibody, CDHOB antibody, OB antibody, OSF-4 antibody, cadherin 11 antibody, cadherin 11, type 2, OB-cadherin (osteoblast) antibody, cadherin 11 S homeolog antibody, CDH11 antibody, cdh11 antibody, Cdh11 antibody, cdh11.S antibody
- Background
-
Description: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
Aliases: OB, CAD11, CDHOB, OSF-4
- Molecular Weight
- 88kDa
- Gene ID
- 1009
- HGNC
- 1009
- UniProt
- P55287
-