OB Cadherin antibody (AA 468-617)

Catalog No. ABIN5542424

Product Details anti-OB Cadherin Antibody

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Binding Specificity: AA 468-617

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This OB Cadherin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purification: purified

Immunogen: Purified recombinant fragment of human CDH11 (AA: 468-617) expressed in E. coli.

Clone: 4E12G10

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for OB Cadherin

Target: OB Cadherin (CDH11) (Cadherin 11 (CDH11))

Alternative Name: CDH11 (CDH11 Products)

Synonyms: cad11 antibody, cdhob antibody, osf-4 antibody, Xcad-11 antibody, MGC108014 antibody, OB-cadherin antibody, cadherin-11 antibody, Cad11 antibody, cdhvn antibody, vnc antibody, CAD11 antibody, CDHOB antibody, OB antibody, OSF-4 antibody, cadherin 11 antibody, cadherin 11, type 2, OB-cadherin (osteoblast) antibody, cadherin 11 S homeolog antibody, CDH11 antibody, cdh11 antibody, Cdh11 antibody, cdh11.S antibody

Background:

Description: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. ,

Aliases: OB, CAD11, CDHOB, OSF-4

Molecular Weight: 88 kDa

Gene ID: 1009

HGNC: 1009