UFD1L antibody (AA 208-307)

Catalog No. ABIN5542400

Product Details anti-UFD1L Antibody

Target: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Binding Specificity: AA 208-307

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UFD1L antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Purpose: UFD1L Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human UFD1L (AA: 208-307) expressed in E. Coli.

Clone: 4F11A4

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for UFD1L

Target: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Alternative Name: UFD1L (UFD1L Products)

Synonyms: UFD1 antibody, Ufd1 antibody, ufd1 antibody, wu:fc55f04 antibody, zgc:92341 antibody, Ufd1l antibody, ubiquitin recognition factor in ER associated degradation 1 antibody, ubiquitin recognition factor in ER-associated degradation 1 antibody, ubiquitin fusion degradation 1 like (yeast) antibody, ubiquitin recognition factor in ER associated degradation 1 S homeolog antibody, ubiquitin fusion degradation protein 1 homolog antibody, Ubiquitin Fusion Degradation (yeast UFD homolog) antibody, UFD1 antibody, Ufd1 antibody, UFD1L antibody, ufd1.S antibody, ufd1l antibody, ufd1 antibody, EHI_125920 antibody, LOC100166745 antibody, LOC100635687 antibody, LOC100648660 antibody, ufd-1 antibody

Background:

Description: The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.

Aliases: UFD1

Molecular Weight: 34.5kDa

Gene ID: 7353

HGNC: 7353

UniProt: Q92890