TTR antibody (AA 1-147)

Catalog No. ABIN5542369

Product Details anti-TTR Antibody

Target: TTR (Transthyretin (TTR))

Binding Specificity: AA 1-147

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TTR antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purpose: TTR Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human TTR (AA: 1-147) expressed in E. Coli.

Clone: 2E10C5

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for TTR

Target: TTR (Transthyretin (TTR))

Alternative Name: TTR (TTR Products)

Synonyms: zgc:103583 antibody, TTR antibody, LOC100226992 antibody, CTS antibody, CTS1 antibody, HsT2651 antibody, PALB antibody, TBPA antibody, AA408768 antibody, AI787086 antibody, D17860 antibody, prealbumin antibody, Lr1 antibody, Tbpa antibody, Prealbumin antibody, xTTR antibody, transthyretin (prealbumin, amyloidosis type I) antibody, transthyretin antibody, Transthyretin antibody, transthyretin (prealbumin, amyloidosis type 1) antibody, transthyretin-like antibody, transthyretin L homeolog antibody, ttr antibody, TTR antibody, vpb38 antibody, MRAD2831_RS38185 antibody, Caci_4246 antibody, LOC100226992 antibody, Ttr antibody, ttr.L antibody

Background:

Description: This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009]

Aliases: CTS, CTS1, PALB, TBPA, HEL111, HsT2651

Molecular Weight: 15.9kDa

Gene ID: 7276

HGNC: 7276

UniProt: P02766

Pathways: Hormone Transport