PKHD1 antibody (AA 3878-4060)

Catalog No. ABIN5542352

Product Details anti-PKHD1 Antibody

Target: PKHD1 (Polycystic Kidney and Hepatic Disease 1 Protein (PKHD1))

Binding Specificity: AA 3878-4060

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This PKHD1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purpose: PKHD1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of mouse PKHD1 (AA: 3878-4060) expressed in E. Coli.

Clone: 8G12A1

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for PKHD1

Target: PKHD1 (Polycystic Kidney and Hepatic Disease 1 Protein (PKHD1))

Alternative Name: PKHD1 (PKHD1 Products)

Synonyms: ARPKD antibody, FCYT antibody, TIGM1 antibody, FPC antibody, Tigm1 antibody, AI118496 antibody, AI182499 antibody, PKHD1, fibrocystin/polyductin antibody, polycystic kidney and hepatic disease 1 antibody, PKHD1 antibody, Pkhd1 antibody

Background:

Description: Mutations in the PKHD1 gene, which encodes fibrocystin, cause autosomal recessive polycystic kidney disease (ARPKD). Unfortunately, the lack of specific antibodies to the mouse protein impairs the study of splicing, post-translational processing, shedding, and temporal and spatial expression of endogenous fibrocystin at the cellular and subcellular level.

Aliases: FPC, Tigm1, AI118496, AI182499

Molecular Weight: 445kDa

Gene ID: 241035

HGNC: 241035

UniProt: E9PZ36