RAB13 antibody (AA 66-200)

Catalog No. ABIN5542349

Product Details anti-RAB13 Antibody

Target: RAB13 (RAB13, Member RAS Oncogene Family (RAB13))

Binding Specificity: AA 66-200

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RAB13 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purpose: Rab13 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human Rab13 (AA: 66-200) expressed in E. Coli.

Clone: 8E8E2

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for RAB13

Target: RAB13 (RAB13, Member RAS Oncogene Family (RAB13))

Alternative Name: Rab13 (RAB13 Products)

Synonyms: cb764 antibody, hm:zeh0455 antibody, RAB13 antibody, 0610007N03Rik antibody, B230212B15Rik antibody, RAB13, member RAS oncogene family antibody, rab13 antibody, RAB13 antibody, Rab13 antibody

Background:

Description: This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12.

Aliases: GIG4

Molecular Weight: 22.8kDa

Gene ID: 5872

HGNC: 5872

UniProt: P51153

Pathways: Cell-Cell Junction Organization