Lamin B2 antibody (AA 401-600)

Catalog No. ABIN5542337

Product Details anti-Lamin B2 Antibody

Target: Lamin B2 (LMNB2)

Binding Specificity: AA 401-600

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Lamin B2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purpose: LMNB2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human LMNB2 (AA: 401-600) expressed in E. Coli.

Clone: 2E2F4

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for Lamin B2

Target: Lamin B2 (LMNB2)

Alternative Name: LMNB2 (LMNB2 Products)

Background:

Description: This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.

Aliases: LMN2, LAMB2

Molecular Weight: 67.7kDa

Gene ID: 84823

HGNC: 84823

UniProt: Q03252

Pathways: Apoptosis, Caspase Cascade in Apoptosis