HDAC6 antibody (AA 482-800)

Catalog No. ABIN5542328

Product Details anti-HDAC6 Antibody

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Binding Specificity: AA 482-800

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HDAC6 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: HDAC6 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human HDAC6 (AA: 482-800) expressed in E. Coli.

Clone: 4G6F9

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for HDAC6

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Alternative Name: HDAC6 (HDAC6 Products)

Background:

Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Aliases: HD6, JM21, CPBHM, PPP1R90

Molecular Weight: 131.4kDa

Gene ID: 10013

HGNC: 10013

UniProt: Q9UBN7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling