HDAC4 antibody (AA 456-592)
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- Target See all HDAC4 Antibodies
- HDAC4 (Histone Deacetylase 4 (HDAC4))
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Binding Specificity
- AA 456-592
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This HDAC4 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Purpose
- HDAC4 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human HDAC4 (AA: 456-592) expressed in E. Coli.
- Clone
- 5E4A5
- Isotype
- IgG1
- Top Product
- Discover our top product HDAC4 Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- HDAC4 (Histone Deacetylase 4 (HDAC4))
- Alternative Name
- HDAC4 (HDAC4 Products)
- Background
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Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Aliases: HD4, AHO3, BDMR, HDACA, HA6116, HDAC-4, HDAC-A
- Molecular Weight
- 119kDa
- Gene ID
- 9759
- HGNC
- 9759
- UniProt
- P56524
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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