FOXP2 antibody (AA 641-740)

Catalog No. ABIN5542318

Product Details anti-FOXP2 Antibody

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Binding Specificity: AA 641-740

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purpose: FOXP2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human FOXP2 (AA: 641-740) expressed in E. Coli.

Clone: 2G11B8

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for FOXP2

Target: FOXP2 (Forkhead Box P2 (FOXP2))

Alternative Name: FOXP2 (FOXP2 Products)

Synonyms: CAGH44 antibody, SPCH1 antibody, TNRC10 antibody, 2810043D05Rik antibody, AI449000 antibody, CAG-16 antibody, D0Kist7 antibody, RGD1559697 antibody, FOXP2 antibody, spch1 antibody, cagh44 antibody, tnrc10 antibody, xlFoxP2 antibody, foxP2 antibody, foxP antibody, Foxp2 antibody, foxP2b antibody, foxp2a antibody, forkhead box P2 antibody, lmw-gs antibody, forkhead box transcription factor antibody, forkhead box P2 L homeolog antibody, FOXP2 antibody, Foxp2 antibody, foxp2 antibody, foxP2 antibody, foxp1c antibody, foxp2.L antibody

Background:

Description: This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

Aliases: SPCH1, CAGH44, TNRC10

Molecular Weight: 80kDa

Gene ID: 93986

HGNC: 93986

UniProt: O15409