BRD2 antibody (AA 227-364)

Catalog No. ABIN5542291

Product Details anti-BRD2 Antibody

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Binding Specificity: AA 227-364

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This BRD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purification: purified

Immunogen: Purified recombinant fragment of human BRD2 (AA: 227-364) expressed in E. coli.

Clone: 7C1B10

Isotype: IgG2b

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: , FCM: 1:200 - 1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for BRD2

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Alternative Name: BRD2 (BRD2 Products)

Synonyms: D6S113E antibody, FSH antibody, FSRG1 antibody, NAT antibody, RING3 antibody, RNF3 antibody, AW228947 antibody, D17H6S113E antibody, Frg-1 antibody, Fsrg-1 antibody, Fsrg1 antibody, Nat antibody, Ring3 antibody, Rnf3 antibody, mKIAA4005 antibody, brd2-a antibody, fsh antibody, fsrg1 antibody, nat antibody, ring3 antibody, rnf3 antibody, brd2 antibody, fe47f02 antibody, fi85h05 antibody, wu:fe47f02 antibody, wu:fi85h05 antibody, Ring3 protein antibody, bromodomain containing 2 antibody, bromodomain containing 2 S homeolog antibody, bromodomain containing 2a antibody, CHLREDRAFT_190116 antibody, CHLREDRAFT_150233 antibody, CHLREDRAFT_182576 antibody, CHLREDRAFT_188250 antibody, BRD2 antibody, Brd2 antibody, brd2.S antibody, brd2a antibody

Background:

Description: This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.,

Aliases: FSH, NAT, RNF3, FSRG1, RING3, D6S113E, O27.1.1

Molecular Weight: 88 kDa

Gene ID: 6046

HGNC: 2101

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection