BRD2 antibody (AA 227-364)

Catalog No. ABIN5542291

Product Details anti-BRD2 Antibody

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Binding Specificity: AA 227-364

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BRD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purpose: BRD2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human BRD2 (AA: 227-364) expressed in E. Coli.

Clone: 7C1B10

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for BRD2

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Alternative Name: BRD2 (BRD2 Products)

Background:

Description: This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.

Aliases: FSH, NAT, RNF3, FSRG1, RING3, D6S113E, O27.1.1

Molecular Weight: 88kDa

Gene ID: 6046

HGNC: 2101

UniProt: P25440

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection