CD4 antibody
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- Target See all CD4 Antibodies
- CD4
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Reactivity
- Horse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD4 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- This anitbody reacts with T-helper cells, it recognises a 58 kDa cell surface glycoprotein that is primarily expressed on a subpopulation of equine T lymphocytes and considered to be the equine homologue of human CD4. Species: Equine (Horse).
- Purification
- Affinity chromatography on Protein G from tissue culture supernatant
- Immunogen
- Equine thymocytes
- Clone
- CVS4
- Isotype
- IgG1
- Top Product
- Discover our top product CD4 Primary Antibody
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- Application Notes
- Flow cytometry : 1/25-1/200, use 10 μL of this working dilution to label 10e6 cells in 100 μL. Immunohistochemistry on Frozen sections. Immunoprecipitation.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Containing 0.09 % Sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
- Expiry Date
- 12 months
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Complex interactions between the major and minor envelope proteins of equine arteritis virus determine its tropism for equine CD3+ T lymphocytes and CD14+ monocytes." in: Journal of virology, Vol. 84, Issue 10, pp. 4898-911, (2010) (PubMed).
: "A point mutation in a herpesvirus polymerase determines neuropathogenicity." in: PLoS pathogens, Vol. 3, Issue 11, pp. e160, (2008) (PubMed).
: "
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Complex interactions between the major and minor envelope proteins of equine arteritis virus determine its tropism for equine CD3+ T lymphocytes and CD14+ monocytes." in: Journal of virology, Vol. 84, Issue 10, pp. 4898-911, (2010) (PubMed).
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- Target
- CD4
- Alternative Name
- cd4 (CD4 Products)
- Synonyms
- cd4 antibody, L3T4 antibody, Ly-4 antibody, CD4mut antibody, W3/25 antibody, p55 antibody, CD4 molecule antibody, carcinoembryonic antigen-related cell adhesion molecule 5 antibody, T-cell surface glycoprotein CD4 antibody, CD4 antigen antibody, Cd4 molecule antibody, CD4 antibody, LOC100125525 antibody, cd4 antibody, Cd4 antibody
- Background
- CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes (helper/inducer T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
- UniProt
- F6Y6X8
- Pathways
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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