CEACAM20 antibody

Catalog No. ABIN5541205

Product Details anti-CEACAM20 Antibody

Target: CEACAM20 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 20 (CEACAM20))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CEACAM20 antibody is un-conjugated

Application: Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS), Enzyme Immunoassay (EIA), ELISA (Capture)

Specificity: Recognizes CEACAM20

Purification: Affinity Chromatography on Protein G.

Immunogen: Genetic immunisation with cDNA encoding Human CEACAM20.

Clone: HT-12D8

Isotype: IgG1

Application Details

Application Notes: Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400. ELISA (capture): With clone HD-6G4-A5 as detection antibody. Flow cytometry: 1.2 μg/10e6 cells. Immunofluorescence: 1 μg/10e6 cells.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered saline, pH 7.2

Storage: 4 °C,-20 °C

Storage Comment: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CEACAM20

Target: CEACAM20 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 20 (CEACAM20))

Alternative Name: ceacam20 (CEACAM20 Products)

Synonyms: UNQ9366 antibody, 9130012D09Rik antibody, carcinoembryonic antigen related cell adhesion molecule 20 antibody, carcinoembryonic antigen-related cell adhesion molecule 20 antibody, CEACAM20 antibody, Ceacam20 antibody

Background: CEA-related cell adhesion molecule 20 (CEACAM20) belongs to the carcinoembryonic antigen (CEA) gene family (1). It encodes a putative glycoprotein which is membrane-bound via a transmembrane domain. The CEACAM20 protein contains a single N domain followed by 4 immunoglobulin-like A (A1, A2) and B (B1, B2) domains. Expression of CEACAM20 can be found in tissues of prostate, testis, duodenum and small intestine with highest expression in prostate. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria. High expression of CEACAM20 in tissue of prostate carcinoma and in prostate carcinoma cell lines suggest that CEACAM20 can be used as a tumor marker.

UniProt: Q6UY09