SSR4 antibody (AA 98-126)

Catalog No. ABIN5538371

Product Details anti-SSR4 Antibody

Target: SSR4 (Signal Sequence Receptor, delta (SSR4))

Binding Specificity: AA 98-126

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSR4 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SSR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the Central region of human SSR4.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SSR4

Target: SSR4 (Signal Sequence Receptor, delta (SSR4))

Alternative Name: SSR4 (SSR4 Products)

Synonyms: TRAPD antibody, AW743063 antibody, C78062 antibody, Trap antibody, signal sequence receptor subunit 4 antibody, signal sequence receptor, delta antibody, SSR4 antibody, Ssr4 antibody

Background: SSR4, also called TRAPD, is assumed to be involved in protein secretion. It is located in the Xq28 region, arranged in a compact head-to-head manner with the IDH3G gene. These two genes are driven by a bidirectional promoter located between them, and encode proteins involved in unrelated biochemical pathways located in different compartments of the cell. The nontranscribed intergenic region represents only 133 bp and is embedded in a CpG island. The CpG island functions as a bidirectional promoter to initiate the transcription of both functionally unrelated genes with distinct expression patterns. SSR4 consists of six exons and is approximately 70 kb telomeric to the ALD gene. Although alternative splicing of exon 5 has not been detected in human SSR4, transcript variants missing the region homologous to human exon 5 have been detected in both Xenopus laevis and Mus musculus.

Molecular Weight: 19 kDa

Gene ID: 6748

UniProt: P51571