Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MUTED antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the Central region of human MUTED.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
BLOS5 antibody, MU antibody, MUTED antibody, muted antibody, 1810074A19Rik antibody, Muted antibody, mu antibody, biogenesis of lysosomal organelles complex 1 subunit 5 antibody, biogenesis of lysosomal organelles complex 1 subunit 5 L homeolog antibody, biogenesis of lysosomal organelles complex-1, subunit 5, muted antibody, BLOC1S5 antibody, bloc1s5.L antibody, Bloc1s5 antibody
Background
This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.