TXNRD3 antibody (AA 304-333)

Catalog No. ABIN5537844

Product Details anti-TXNRD3 Antibody

Target: TXNRD3 (Thioredoxin Reductase 3 (TXNRD3))

Binding Specificity: AA 304-333

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNRD3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TXNRD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the Central region of human TXNRD3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TXNRD3

Target: TXNRD3 (Thioredoxin Reductase 3 (TXNRD3))

Alternative Name: TXNRD3 (TXNRD3 Products)

Synonyms: MGC81848 antibody, MGC147163 antibody, TGR antibody, TR2 antibody, TRXR3 antibody, AI196535 antibody, Tgr antibody, thioredoxin reductase 3 antibody, apoptosis-inducing factor 3 antibody, thioredoxin reductase 3 L homeolog antibody, TXNRD3 antibody, LOC413958 antibody, txnrd3.L antibody, txnrd3 antibody, Txnrd3 antibody

Background: This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 71 kDa

Gene ID: 114112

UniProt: Q86VQ6

Pathways: Cell RedoxHomeostasis