SHMT1 antibody (N-Term)

Catalog No. ABIN5537530

Product Details anti-SHMT1 Antibody

Target: SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

Binding Specificity: AA 19-47, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHMT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SHMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-47 amino acids from the N-terminal region of human SHMT1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SHMT1

Target: SHMT1 (serine Hydroxymethyltransferase 1 (Soluble) (SHMT1))

Alternative Name: SHMT1 (SHMT1 Products)

Synonyms: Shmt antibody, mShmt antibody, LRRGT00032 antibody, shmt1 antibody, MGC53442 antibody, zgc:66171 antibody, zgc:77524 antibody, SHMT1 antibody, Shmt1 antibody, CSHMT antibody, SHMT antibody, AI324848 antibody, AI385541 antibody, C81125 antibody, mshmt antibody, mshmt1 antibody, mshmt2 antibody, MEL-32 antibody, SHMT2 antibody, F20D10.50 antibody, F20D10_50 antibody, SERINE HYDROXYMETHYLTRANSFERASE 1 antibody, SERINE TRANSHYDROXYMETHYLASE antibody, SERINE TRANSHYDROXYMETHYLTRANSFERASE antibody, STM antibody, serine transhydroxymethyltransferase 1 antibody, serine hydroxymethyltransferase 1 antibody, serine hydroxymethyltransferase 1 (soluble) L homeolog antibody, serine hydroxymethyltransferase 1 (soluble) antibody, microRNA 6778 antibody, serine transhydroxymethyltransferase 1 antibody, Shmt1 antibody, shmt1.L antibody, shmt1 antibody, MIR6778 antibody, SHMT1 antibody, SHM1 antibody

Background: This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.

Molecular Weight: 53 kDa

Gene ID: 6470

UniProt: P34896