SEC63 antibody (N-Term)
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- Target See all SEC63 Antibodies
- SEC63 (SEC63 Homolog (SEC63))
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Binding Specificity
- AA 139-168, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SEC63 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This SEC63 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-168 amino acids from the N-terminal region of human SEC63.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SEC63 Primary Antibody
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- Application Notes
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- SEC63 (SEC63 Homolog (SEC63))
- Alternative Name
- SEC63 (SEC63 Products)
- Synonyms
- DNAJC23 antibody, ERdj2 antibody, PRO2507 antibody, SEC63L antibody, 5730478J10Rik antibody, AI649014 antibody, AW319215 antibody, SEC63-like antibody, zgc:92718 antibody, SEC63 homolog, protein translocation regulator antibody, SEC63-like (S. cerevisiae) antibody, SEC63 homolog, protein translocation regulator L homeolog antibody, SEC63 antibody, Sec63 antibody, sec63 antibody, sec63.L antibody
- Background
- The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
- Molecular Weight
- 88 kDa
- Gene ID
- 11231
- UniProt
- Q9UGP8
- Pathways
- ER-Nucleus Signaling
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