PDE11A antibody (N-Term)

Catalog No. ABIN5537471

Product Details anti-PDE11A Antibody

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Binding Specificity: AA 34-63, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE11A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PDE11A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-63 amino acids from the N-terminal region of human PDE11A.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PDE11A

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Alternative Name: PDE11A (PDE11A Products)

Synonyms: PPNAD2 antibody, 6330414F14Rik antibody, A630086N24Rik antibody, Gm350 antibody, PDE11A1 antibody, si:ch211-222f23.5 antibody, PDE11A antibody, ppnad2 antibody, Pde11a antibody, phosphodiesterase 11A antibody, phosphodiesterase 11a antibody, dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A antibody, PDE11A antibody, Pde11a antibody, pde11a antibody, LOC100470038 antibody

Background: The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 105 kDa

Gene ID: 50940

UniProt: Q9HCR9

Pathways: cAMP Metabolic Process