DGKA antibody (C-Term)

Catalog No. ABIN5536026

Product Details anti-DGKA Antibody

Target: DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

Binding Specificity: AA 598-628, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DGKA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This DGKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 598-628 amino acids from the C-terminal region of human DGKA.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for DGKA

Target: DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

Alternative Name: DGKA (DGKA Products)

Synonyms: DAGK antibody, DAGK1 antibody, DGK-alpha antibody, 80kDa antibody, AW146112 antibody, Dagk1 antibody, dgka antibody, zgc:136759 antibody, dagk antibody, dagk1 antibody, dgk-alpha antibody, diacylglycerol kinase alpha antibody, diacylglycerol kinase, alpha antibody, diacylglycerol kinase, alpha 80kDa antibody, diacylglycerol kinase, alpha a antibody, diacylglycerol kinase alpha S homeolog antibody, DGKA antibody, Dgka antibody, dgkaa antibody, Tsp_02164 antibody, dgka antibody, dgka.S antibody

Background: Upon cell stimulation, the kinase DGKA converts the second messenger diacylglycerol into phophatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity. DGKA is stimulated by calcium and phosphatidylserine, and is phosphorylated by protein kinase C. Tissue expression is in lymphocytes and oligodengroglial cells. DGKA contains 2 zinc-dependent phorbol-ester and DAG binding domains, and 2 EF-hand calcium binding domains.

Molecular Weight: 83 kDa

Gene ID: 1606

UniProt: P23743