GAB3 antibody (N-Term)

Catalog No. ABIN5535937

Product Details anti-GAB3 Antibody

Target: GAB3 (GRB2-Associated Binding Protein 3 (GAB3))

Binding Specificity: AA 30-58, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAB3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GAB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the N-terminal region of human GAB3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for GAB3

Target: GAB3 (GRB2-Associated Binding Protein 3 (GAB3))

Alternative Name: GAB3 (GAB3 Products)

Synonyms: 5930433H21Rik antibody, GRB2 associated binding protein 3 antibody, growth factor receptor bound protein 2-associated protein 3 antibody, GAB3 antibody, gab3 antibody, Gab3 antibody

Background: GAB3 is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 66 kDa

Gene ID: 139716

UniProt: Q8WWW8