WDR11 antibody (AA 544-572)

Catalog No. ABIN5535764

Product Details anti-WDR11 Antibody

Target: WDR11 (WD Repeat Domain 11 (WDR11))

Binding Specificity: AA 544-572

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR11 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BRWD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 544-572 amino acids from the Central region of human BRWD2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for WDR11

Target: WDR11 (WD Repeat Domain 11 (WDR11))

Alternative Name: BRWD2 (WDR11 Products)

Synonyms: Brwd2 antibody, WDR11 antibody, PHIP antibody, BRWD2 antibody, DR11 antibody, HH14 antibody, WDR15 antibody, 2900055P10Rik antibody, AW489876 antibody, mKIAA1351 antibody, WD repeat domain 11 antibody, Wdr11 antibody, WDR11 antibody

Background: WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10,19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.

Molecular Weight: 137 kDa

Gene ID: 55717

UniProt: Q9BZH6