APIP antibody (AA 111-142)
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- Target See all APIP Antibodies
- APIP (APAF1 Interacting Protein (APIP))
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Binding Specificity
- AA 111-142
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This APIP antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This APIP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 111-142 amino acids from the Central region of human APIP.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product APIP Primary Antibody
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- Application Notes
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For IHC-P starting dilution is: 1:25
For WB starting dilution is: 1:2000 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- APIP (APAF1 Interacting Protein (APIP))
- Alternative Name
- APIP (APIP Products)
- Synonyms
- APIP2 antibody, CGI29 antibody, MMRP19 antibody, dJ179L10.2 antibody, hAPIP antibody, CGI-29 antibody, Mmrp19 antibody, RGD1564562 antibody, zgc:103619 antibody, APAF1 interacting protein antibody, APAF1 interacting protein S homeolog antibody, APIP antibody, Apip antibody, apip antibody, apip.S antibody
- Background
- Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.
- Molecular Weight
- 27 kDa
- Gene ID
- 51074
- UniProt
- Q96GX9
- Pathways
- Methionine Biosynthetic Process
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