AARS2 antibody (N-Term)

Catalog No. ABIN5535430

Product Details anti-AARS2 Antibody

Target: AARS2 (Alanyl-tRNA Synthetase 2, Mitochondrial (AARS2))

Binding Specificity: AA 61-91, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AARS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This AlaRS (AARS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-91 amino acids from the N-terminal region of human AlaRS (AARS).

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for AARS2

Target: AARS2 (Alanyl-tRNA Synthetase 2, Mitochondrial (AARS2))

Alternative Name: AlaRS (AARS2 Products)

Synonyms: AARSL antibody, COXPD8 antibody, MT-ALARS antibody, MTALARS antibody, Aarsl antibody, AlaRS antibody, Gm89 antibody, alanyl-tRNA synthetase 2, mitochondrial antibody, AARS2 antibody, Aars2 antibody

Background: The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases,of the class II enzymes.Class II tRNA synthases evolved early in evolution and are highly conserved.This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41 % identity witht the E.coli protein.tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons.They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.

Molecular Weight: 107 kDa

Gene ID: 16

UniProt: P49588