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CRYGB antibody (AA 68-97)

CRYGB Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5535119
  • Target See all CRYGB Antibodies
    CRYGB (Crystallin, gamma B (CRYGB))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 1
    • 1
    AA 68-97
    Reactivity
    • 14
    • 1
    • 1
    Human
    Host
    • 15
    Rabbit
    Clonality
    • 15
    Polyclonal
    Conjugate
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    This CRYGB antibody is un-conjugated
    Application
    • 15
    • 12
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CRYGB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-97 amino acids from the Central region of human CRYGB.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CRYGB Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    CRYGB (Crystallin, gamma B (CRYGB))
    Alternative Name
    CRYGB (CRYGB Products)
    Synonyms
    MGC64303 antibody, cryg2 antibody, MGC85383 antibody, MGC146522 antibody, CRYG2 antibody, CTRCT39 antibody, Cryg-3 antibody, DGcry-3 antibody, Nop antibody, Cryg2 antibody, Len antibody, crystallin, gamma B antibody, crystallin gamma B L homeolog antibody, crystallin gamma B antibody, crygb antibody, crygb.L antibody, CRYGB antibody, Crygb antibody
    Background
    Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.
    Molecular Weight
    21 kDa
    Gene ID
    1419
    UniProt
    P07316
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