Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Immunogen
This CAMK2D (CAMK2 delta) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 448-478 amino acids from the C-terminal region of human CAMK2D (CAMK2 delta).
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
CAMK2D
(Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D))
CAMKD antibody, CAMK1 antibody, Camk2 antibody, Camki antibody, RATCAMKI antibody, camk2 antibody, camkd antibody, camkII antibody, 2810011D23Rik antibody, 8030469K03Rik antibody, [d]-CaMKII antibody, mKIAA4163 antibody, calcium/calmodulin dependent protein kinase II delta antibody, calcium/calmodulin-dependent protein kinase II delta antibody, calcium/calmodulin dependent protein kinase (CaM kinase) II delta S homeolog antibody, calcium/calmodulin dependent protein kinase (CaM kinase) II delta antibody, calcium/calmodulin-dependent protein kinase II, delta antibody, CAMK2D antibody, Camk2d antibody, camk2d.S antibody, camk2d antibody
Background
CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Expression of CAMK2 delta is significantly increased in patients suffering from dilated cardiomyopathy.