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SOCS6 antibody (N-Term)

SOCS6 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5532198
  • Target See all SOCS6 Antibodies
    SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    AA 40-69, N-Term
    Reactivity
    • 34
    • 27
    • 15
    • 1
    Human
    Host
    • 45
    • 3
    • 1
    Rabbit
    Clonality
    • 48
    • 1
    Polyclonal
    Conjugate
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SOCS6 antibody is un-conjugated
    Application
    • 38
    • 22
    • 21
    • 13
    • 13
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SOCS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human SOCS6.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SOCS6 Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))
    Alternative Name
    SOCS6 (SOCS6 Products)
    Synonyms
    CIS-4 antibody, CIS4 antibody, HSPC060 antibody, SOCS-4 antibody, SOCS-6 antibody, SOCS4 antibody, SSI4 antibody, STAI4 antibody, STATI4 antibody, socs6 antibody, MGC81477 antibody, SOCS6 antibody, 1500012M23Rik antibody, 5830401B18Rik antibody, AI447482 antibody, Cis4 antibody, Cish4 antibody, Socs4 antibody, socs6l antibody, zgc:64107 antibody, wu:fb77f06 antibody, suppressor of cytokine signaling 6 antibody, suppressor of cytokine signaling 6 L homeolog antibody, suppressor of cytokine signaling antibody, suppressor of cytokine signaling 6b antibody, SOCS6 antibody, Socs6 antibody, socs6.L antibody, socs6 antibody, socs6b antibody
    Background
    The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
    Molecular Weight
    60 kDa
    Gene ID
    9306
    UniProt
    O14544
    Pathways
    JAK-STAT Signaling, Carbohydrate Homeostasis
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