QPRT antibody (C-Term)

Catalog No. ABIN5531984

Product Details anti-QPRT Antibody

Target: QPRT (Quinolinate Phosphoribosyltransferase (QPRT))

Binding Specificity: AA 206-234, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QPRT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This QPRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the C-terminal region of human QPRT.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for QPRT

Target: QPRT (Quinolinate Phosphoribosyltransferase (QPRT))

Alternative Name: QPRT (QPRT Products)

Synonyms: ECK0108 antibody, JW0105 antibody, VF2184 antibody, QPRTase antibody, 2410027J01Rik antibody, AI647766 antibody, quinolinate phosphoribosyltransferase antibody, nicotinate-nucleotide pyrophosphorylase antibody, nicotinate-nucleotide diphosphorylase antibody, carboxylating antibody, ECs0113 antibody, nadC antibody, VP2522 antibody, STY0167 antibody, BJE04_RS13210 antibody, QPRT antibody, Qprt antibody

Background: This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.

Molecular Weight: 31 kDa

Gene ID: 23475

UniProt: Q15274