Desmocollin 1 antibody (C-Term)

Catalog No. ABIN5531058

Product Details anti-Desmocollin 1 Antibody

Target: Desmocollin 1 (DSC1)

Binding Specificity: AA 659-687, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmocollin 1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 659-687 amino acids from the C-terminal region of human DSC1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Desmocollin 1

Target: Desmocollin 1 (DSC1)

Alternative Name: DSC1 (DSC1 Products)

Synonyms: DSC1 antibody, CDHF1 antibody, DG2/DG3 antibody, DSC1b antibody, DG2DG3 antibody, dg3 antibody, Dsc1a antibody, Dsc1b antibody, desmocollin 1 antibody, DSC1 antibody, Dsc1 antibody

Background: DSC1 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined.

Molecular Weight: 100 kDa

Gene ID: 1823

UniProt: Q08554