CD300E antibody

Catalog No. ABIN5526907

Product Details anti-CD300E Antibody

Target: CD300E (CD300e Molecule (CD300E))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD300E antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Specificity: The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.

Cross-Reactivity (Details): Human

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Endotoxin Level: Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

Immunogen: CD300e-HA-transfected cells

Clone: UP-H2

Isotype: IgG1 kappa

Application Details

Application Notes: Functional application: Stimulation.
Flow cytometry: Recommended dilution: 1-4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Preservative: Azide free

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for CD300E

Target: CD300E (CD300e Molecule (CD300E))

Alternative Name: CD300e (CD300E Products)

Synonyms: BC034097 antibody, CLM2 antibody, Cd300le antibody, TREM5 antibody, CD300LE antibody, CLM-2 antibody, CMRF35-A5 antibody, IREM-2 antibody, IREM2 antibody, PIgR-2 antibody, PIgR2 antibody, CD300E molecule antibody, CD300e molecule antibody, Cd300e antibody, CD300E antibody

Background: CD300e molecule,CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.,CLM2, CMRF35-A5, LMIR6, IREM-2, PlgR2

Gene ID: 342510

UniProt: Q496F6