TFF3 antibody (AA 23-81)

Catalog No. ABIN5519063

Product Details anti-TFF3 Antibody

Target: TFF3 (Trefoil Factor 3 (Intestinal) (TFF3))

Binding Specificity: AA 23-81

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFF3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for TFF3 detection. Tested with WB, IHC-P, Direct ELISA in Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for TFF3 detection. Tested with WB, IHC-P, Direct ELISA in Mouse,Rat.
Gene Name: trefoil factor 3
Protein Name: Trefoil factor 3

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived rat TFF3 recombinant protein (Position: Q23-F81).

Isotype: IgG

Application Details

Application Notes: Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for TFF3

Target: TFF3 (Trefoil Factor 3 (Intestinal) (TFF3))

Alternative Name: Tff3 (TFF3 Products)

Synonyms: TFF3 antibody, ITF antibody, P1B antibody, TFI antibody, mITF antibody, trefoil factor 3 antibody, trefoil factor 3, intestinal antibody, TFF3 antibody, Tff3 antibody

Background: Trefoil factor 3 is a protein that in humans is encoded by the TFF3 gene. It is mapped to 21q22.3. Members of the trefoil family can interact with mucins and have an influence on mucus viscosity. They also promote migration of epithelial cells, are linked to antiapoptosis, induce cell scattering, trigger chemotaxis, and participate in immune responses. This gene is a marker of columnar epithelium and is expressed in a variety of tissues including goblet cells of the intestines and colon. It has been found that TFF3 is the most highly upregulated gene in 19 poorly differentiated endometrioid endometrial carcinomas (G3-EECs) compared with normal endometrium biopsies.

Synonyms: Trefoil factor 3, Intestinal trefoil factor, rITF, Polypeptide P1.B, rP1.B, Tff3, Itf

Gene ID: 25563

UniProt: Q03191